CYCLIC RGD PEPTIDE-MODIFIED LIPOSOMAL DRUG DELIVERY SYSTEM: ENHANCED CELLULAR UPTAKE IN VITRO AND IMPROVED PHARMACOKINETICS IN RATS

Cyclic RGD peptide-modified liposomal drug delivery system: enhanced cellular uptake in vitro and improved pharmacokinetics in rats

Zhongya Chen,1,2 Jiaxin Deng,1,2 Yan Zhao,1,2 Tao Tao1,21National Pharmaceutical Engineering Research Center, 2Shanghai Institute of Pharmaceutical Industry, China State Institute of Pharmaceutical Industry, Shanghai, People's Republic Left Side Cover of ChinaBackground: Integrins αvβ3 and αvβ5, both of

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CT-P13: design, development, and place in therapy

Tommaso Gabbani,1 Simona Deiana,2 Vito Annese3 1Gastroenterology Unit, Morgagni-Pierantoni Hospital, AUSL Romagna, Forlì, Incontinence/Catheters 2Division of Gastroenterology, AOU Careggi University Hospital, Florence, Italy; 3Gastroenterology Department, Valiant Clinic, Dubai, UAE Abstract: The introduction of biological agents has revoluti

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SAMMY-seq reveals early alteration of heterochromatin and deregulation of bivalent genes in Hutchinson-Gilford Progeria Syndrome

Hutchinson-Gilford progeria syndrome Left Side Cover is a genetic disease where an aberrant form of Lamin A disrupts chromatin by interfering with lamina associated domains.Here, the authors present the SAMMY-seq, a Bike Units - Dual Sport method for genome-wide characterization of heterochromatin dynamics and detect early stage alterations of hete

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